The Lancet. Infectious Diseases - Cephas Health Research Initiative Inc. https://cephashri.org Advancing Evidence. Building Healthier Communities Thu, 30 Oct 2025 23:25:45 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://cephashri.org/wp-content/uploads/2025/10/cropped-favicon-32x32.png The Lancet. Infectious Diseases - Cephas Health Research Initiative Inc. https://cephashri.org 32 32 Global, regional, and national burden of upper respiratory infections and otitis media, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021 https://cephashri.org/publication/global-regional-and-national-burden-of-upper-respiratory-infections-and-otitis-media-1990-2021-a-systematic-analysis-from-the-global-burden-of-disease-study-2021/ Thu, 30 Oct 2025 23:25:45 +0000 https://cephashri.org/?post_type=publication&p=1121 Background
Upper respiratory infections (URIs) are the leading cause of acute disease incidence worldwide and contribute to a substantial health-care burden. Although acute otitis media is a common complication of URIs, the combined global burden of URIs and otitis media has not been studied comprehensively. We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to explore the fatal and non-fatal burden of the two diseases across all age groups, including a granular analysis of children younger than 5 years, in 204 countries and territories from 1990 to 2021.

Methods
Mortality due to URIs and otitis media was estimated with use of vital registration and sample-based vital registration data, which are used as inputs to the Cause of Death Ensemble model to separately model URIs and otitis media mortality by age and sex. Morbidity was modelled with a Bayesian...

The post Global, regional, and national burden of upper respiratory infections and otitis media, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021 first appeared on Cephas Health Research Initiative Inc..

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Upper respiratory infections (URIs) are the leading cause of acute disease incidence worldwide and contribute to a substantial health-care burden. Although acute otitis media is a common complication of URIs, the combined global burden of URIs and otitis media has not been studied comprehensively. We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to explore the fatal and non-fatal burden of the two diseases across all age groups, including a granular analysis of children younger than 5 years, in 204 countries and territories from 1990 to 2021.

Methods
Mortality due to URIs and otitis media was estimated with use of vital registration and sample-based vital registration data, which are used as inputs to the Cause of Death Ensemble model to separately model URIs and otitis media mortality by age and sex. Morbidity was modelled with a Bayesian...

The post Global, regional, and national burden of upper respiratory infections and otitis media, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021 first appeared on Cephas Health Research Initiative Inc..

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